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Atorvastatin is a prescription name that is better known as Lipitor. It is a medication that is sold by Pfizer and is indicated in the treatment of high cholesterol. The medication is part of a class of drugs known as statins. Lipitor is also known to stabilize plaque, which can help to prevent strokes. Lipitor works by inhibiting HMG-CaA reductase, which is a liver enzyme that is known to profoundly impact the production of cholesterol in the body of a human being.
Lipitor was first developed in 1985 by Bruce Roth, who was employed by Parke-Davis Warner Lambert Company, which is now known as Pfizer. It was then approved by the United States Food and Drug Administration and has been in wide use ever since. In 2008 Lipitor sales reached $12.4 billion making it the highest selling branded pharmaceutical in the world. The US patent on this medication is going to expire in June of 2011, although a deal has been reached to delay a generic form of the medication until November of 2011. The generic will be greatly appreciated by the growing number of consumers purchasing this medication.
Lipitor has been found to be effective in the treatment of many conditions and is often used in the treatment of hypercholesterolemia, heterozygous familial hypercholesterolemia, homozygous familial hypercholesterolemia, as well as Fredrickson Type IV and Fredrickson Type III. Lipitor is also indicated for the combined treatment of hyperlipidemia, a prophylaxis for coronary heart disease, as well as stroke prophylaxis for patients with type II diabetes.
While Lipitor is a very effective medication, it is not a medication that is safe for consumption by all patients. Those who should not take Lipitor include those with active liver disease, unexplained elevations of AST or ALT levels, as well as those who are pregnant or breastfeeding. As is the case with all medications, Lipitor may cause some unintended side effects. These side effects include headache, weakness, dizziness, insomnia, rash, chest pain, abdominal discomfort, urinary tract infection, back pain, sinusitis, and allergic reaction. Patients should discuss side effects as they occur so the doctor can determine if the use of Lipitor is still the best medication for the patient.
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